姓 名：向 浩
职 称：教授/博士生导师
职 务：武汉大学公共卫生学院全球健康学系主任
武汉大学全球健康研究中心副主任
招生方向: 环境流行病学(博士)
环境流行病学(学硕)
公共卫生硕士(专硕)
Email：xianghao@whu.edu.cn
个人简介：
向浩，教授，博士生导师，湖北省公共卫生青年拔尖人才，武汉大学珞珈青年学者。主要研究方向为环境流行病学和全球健康学。近年主持各级各类项目超过20项(国家自然科学基金(2项)，美国梅琳达-盖茨基金会项目(2项)，湖北省自然科学基金面上项目(1项)，湖北省教育厅教学改革项目(3项)，人才项目 (3项))，累计到账经费超过500万元。以第一和通讯作者发表SCI/SSCI论文50余篇，超过20篇论文发表于Environmental Science & Technology，Journal of Hazardous Materials，Environment International和Science of the Total Environment等SCI/SSCI 1区杂志，累计被引用超过2000次，ESI高被引论文2篇，H指数为28。2018年主笔的咨询报告《关于疫苗风险点防控的对策建议》和《我省专家对加强疫苗监督管理的工作建议》分别被中共中央办公厅采纳和湖北省委书记批示，新冠肺炎疫情期间参与撰写的6项咨询报告获中央和省级领导批示，其中《关于降低武汉市新冠肺炎病死率的建议》获得李克强总理的肯定性批示。
科研方面，长期围绕环境健康和健康中国开展研究，主要在三个领域推进创新：(1) 空气污染与慢性病：基于遥感信息技术和人群健康大数据，构建环境健康风险评估模型，在国内首次系统评估PM1，PM2.5和NO2等空气污染物对高血压、糖尿病和血脂异常等慢性疾病的影响，研究结果为完善大气污染的精准防控政策提供重要依据；(2) 空气污染与母婴健康：构建PM2.5、PM10和NO2等空气污染物的个体暴露模型，明确空气污染是早产和低出生体重等多种母婴疾病的重要危险因素，研究结果先后被Nature (IF=42.779)，Lancet Global Health (IF=21.597)和Environment Health Perspectives (IF=8.341)等国际权威期刊累计引用136次，在该研究领域产生较大的国际影响；(3) 健康中国的实现策略：围绕“健康中国2030规划纲要”的相关目标，深入分析实现健康中国过程中可能面临的主要挑战，并就儿童营养、妇幼和生殖健康、结核病和慢性病四大重点领域展提出相应对策建议，是国内首个基于循证数据全面深入研究健康中国实现的策略研究，研究结果为推进落实健康中国2030提供理论参考和循证依据。参编的学术专著“实现健康中国2030目标——基于实证的研究”，由卫生健康领域的权威出版社“人民卫生出版社”出版。
教学方面，主持湖北省教育厅教学改革项目2项（“基于HEdPREF量表的全球健康本科专业教学质量评价研究”和“基于德尔菲法的全球健康学本科专业课程体系评价指标的构建”）；以通讯作者发表教学改革论文13篇（含SCI收录论文3篇），4篇论文获武汉大学优秀教学论文一等奖；主编教学改革专著《基于全球健康视野的本科教育改革与创新》，参编《现代流行病学》、《现场流行病学》和《预防医学案例版》等人民卫生出版社规划教材4部；教学成果“全球健康视野的公共卫生本科教育改革与创新”获得2018年第8届湖北省高等学校教学成果奖一等奖（个人排名第3），2016年和2014年分获武汉大学教学成果奖一等奖（个人排名第2和第4）。
学术兼职包括国家自然科学基金项目通讯评审专家，教育部学位中心论文评阅专家，中国全球健康大学联盟（CCUGH）第五届理事会主席，中华预防医学会全球卫生分会委员，中国全球卫生网络理事，湖北省预防医学会理事，湖北省预防医学会流行病学专业委员会委员。担任BMC Public Health副主编，Global Health Research and Policy和Global Health Journal编委，中华疾病预防控制杂志(CSCD)编委，气候变化研究进展(CSCD)编委，PNAS，Lancet Planetary Health, ES&T, Environmental International等50多个期刊的审稿人。
一、教育背景
2004–2009，华中科技大学，公共卫生学院流行病与卫生统计学系，博士
1999–2004，华中科技大学，公共卫生学院预防医学专业，学士
二、工作经历
2020/11至今,武汉大学公共卫生学院，教授，博士生导师
2013/11-2020/10，武汉大学公共卫生学院，副教授，硕士生导师
2011/08–2012/09，美国匹兹堡大学，公共卫生学院流行病学系，访问学者
2009/07–2013/10，武汉大学公共卫生学院，流行病与卫生统计学系，讲师
三、主要研究方向：
1. 环境流行病学：气候变化和空气污染的健康效应及机制研究。
2. 全球健康学：全民健康覆盖，卫生政策与卫生体系研究。
四、主持的代表性课题
1. 国家自然科学基金面上项目“大气臭氧暴露对糖尿病肾病的影响及DNA甲基 化机制研究”(42375181), 起止时间：2024.1-2027.12
2. 中央高校基本科研项目(学科交叉团队建设和培育专项项目)“大气臭氧暴露与心血管代谢疾病的关联及机制研究”(2042024kf0023)，起止时间：2024.1-2024.12
3. 盖茨基金会项目“在中国实现健康相关可持续发展目标：开发循证政策行动建议”(OPP1148464), 起止时间：2016.10-2018.10；
4. 盖茨基金会项目“基于国内外比较分析完善中国医疗保险体系”(OPP1199760), 起止时间：2019.1-2019.12；
5. 国家自然科学基金青年基金项目“BER通路基因miRNA结合位点基因多态性与结直肠癌易感性的关联及功能研究”(81402743)， 起止时间：2015.1-2017.12；
6. 湖北省自然科学基金面上项目“CircRNA-MYLK结合miR-19调控PTEN基因在结直肠癌中作用及机制研究”(No.2018CFB634)，起止时间：2018.1-2019.12；
7. 美国中华医学基金会(CMB)教学研究项目“基于胜任力的全球健康人才培养实践和理论探索”（13-134），起止时间：2013.01-2017.12
8. 中央高校基本科研项目(自主科研学科交叉类) “基于遥感的细颗粒物暴露对心血管疾病急性效应的影响研究”(2042016kf0165) , 起止时间：2016.1-2017.12
9. 湖北省高等学校省级教学改革研究项目 “基于HEdPERF量表的全球健康本科专业教学质量评价研究”(2018JG064), 起止时间：2018.7-2020.7
10. 湖北省高等学校省级教学改革研究项目 “基于德尔菲法的全球健康学专业课程体系评价指标的构建”，起止时间：2015.1-2016.12
五、代表性论文 ：
1. Shouxin Peng, Zhaoyuan Li, John S. Ji, Bingbing Chen, Xiaoyi Yin, Wei Zhang, Feifei Liu, Huanfeng Shen*, Hao Xiang*. Interaction between Extreme Temperature Events and Fine Particulate Matter on Cardiometabolic Multimorbidity: Evidence from Four National Cohort Studies. Environmental Science & Technology (IF:10.8) 2024
2. Zhang, Ke; Chen, Gongbo; He, Jie; Chen, Zhongyang; Pan, Mengnan; Tong, Jiahui; Liu, Feifei*; Xiang, Hao*. DNA methylation mediates the effects of PM2.5 and O3 on ceramide metabolism A novel mechanistic link between air pollution and insulin resistance. Journal of Hazardous Materials. (IF:13.6) 2024
3. Jia hui Tong , Ke Zhang , Zhongyang Chen , Meng nan Pan , Huanfeng Shen , Feifei Liu,*and Hao Xiang*. Effects of short- and long-term exposures to multiple air pollutants on depression among the labor force: A nationwide longitudinal study in China. Science of the Total Environment. (IF: 9.8) 2024
4. Liang, Wei; Li, Ruihan; Chen, Gongbo; Ma, Hongfei; Han, Aojing; Hu, Qilin; Xie, Nianhua; Wei, Jing; Shen, Huanfeng; Wang, Xia*; Xiang, Hao*. Long-term exposure to ambient particulate matter is associated with prognosis in people living with HIV AIDS Evidence from a longitudinal study. Science of the Total Environment. (IF: 9.8) 2024
5. Peng, Shouxin; Yin, Xiaoyi; Chen, Gongbo; Sun, Jinhui; Chen, Bingbing; Zhou, Yi; Li, Zhaoyuan; Liu, Feifei; Xiang, Hao*. Long-term exposure to varying-sized particulate matters and kidney disease in middle-aged and elder adults_A 8-year nationwide cohort study in China. Science of the Total Environment. (IF: 9.8) 2024
6. Pan, Mengnan; Liu, Feifei; Zhang, Ke; Chen, Zhongyang; Tong, Jiahui; Wang, Xiangxiang; Zhou, Feng; Xiang, Hao*. Independent and interactive associations between greenness and ambient pollutants on novel glycolipid metabolism biomarkers_A national repeated measurement study. Environmental Research (IF: 8.3) 2023
7. Liu, Feifei; Zhou, Feng; Zhang, Ke; Wu, Tingting; Pan, Mengnan; Wang, Xiangxiang; Tong, Jiahui; Chen, Zhongyang; Xiang, Hao*. Effects of air pollution and residential greenness on sleep disorder A 8-year nationwide cohort study. Environmental Research (IF: 8.3) 2023
8. Li, Zhaoyuan; Peng, Shouxin; Chen, Meijin; Sun, Jinhui; Liu, Feifei; Wang, Huaiji*; Xiang, Hao*. Associations of fine particulate matter and its metal constituents with blood pressure a panel study during the seventh World Military Games. Environmental Research (IF: 8.3) 2023
9. Wei Liang, Xia Wang, Nianhua Xie, Han Yan, Hongfei Ma, Manqing Liu, Wenhua Kong, Zerong Zhu, Wenjuan Bai, Hao Xiang*. Short-term associations of PM2.5 and PM2.5 constituents with immune biomarkers A panel study in people living with HIV or AIDS. Environmental Pollution (IF: 8.9) 2023
10. Peng, Shouxin; Chen, Bingbing; Li, Zhaoyuan; Sun, Jinhui; Liu, Feifei; Yin, Xiaoyi; Zhou, Yi; Shen, Huanfeng*; Xiang, Hao*. Ambient ozone pollution impairs glucose homeostasis and contributes to renal function decline_population-based evidence. Ecotoxicology and Environmental Safety (IF:6.8) 2023
11. Jiang J, Chen G, Li B, Li N, Liu F, Lu Y, Guo Y, Li S, Chen L, Xiang H*. Associations of residential greenness with hypertension and blood pressure in a Chinese rural population: a cross-sectional study. Environ Sci Pollut Res Int. (IF:4.223) 2021 May 14. doi: 10.1007
12. Liu F, Chen X, Liu Y, Niu Z, Tang H, Mao S, Li N, Chen G, Xiang H*. Serum cardiovascular-related metabolites disturbance exposed to different heavy metal exposure scenarios. J Hazard Mater (IF: 10.588). 2021 Aug 5;415:125590. doi: 10.1016/j.jhazmat.2021.125590.
13. Yan Y, Chen X, Guo Y, Wu C, Zhao Y, Yang N, Dai J, Gong J, Xiang H*. Ambient air pollution and cerebrovascular disease mortality: an ecological time-series study based on 7-year death records in central China. Environ Sci Pollut Res Int. (IF:4.223). 2021 Jun;28(21):27299-27307. doi: 10.1007/s11356-021-12474-z.
14. Niu Z, Liu F, Yu H, Wu S, Xiang H*. Association between exposure to ambient air pollution and hospital admission, incidence, and mortality of stroke: an updated systematic review and meta-analysis of more than 23 million participants. Environ Health Prev Med. (IF:3.674) 2021 Jan 26;26(1):15. doi: 10.1186/s12199-021-00937-1.
15. Li R, Chen G, Jiao A, Lu Y, Guo Y, Li S, Wang C, Xiang H*. Residential Green and Blue Spaces and Type 2 Diabetes Mellitus: A Population-Based Health Study in China. Toxics. (IF:4.146) 2021 Jan 16;9(1):11. doi: 10.3390/toxics9010011.
16. Niu Z, Liu F, Li B, Li N, Yu H, Wang Y, Tang H, Chen X, Lu Y, Cheng Z, Liu S, Chen G, Zhang Y, Xiang H*. Acute effect of ambient fine particulate matter on heart rate variability: an updated systematic review and meta-analysis of panel studies. Environ Health Prev Med. (IF:3.674) 2020 Dec 1;25(1):77. doi: 10.1186/s12199-020-00912-2.
17. Tang H, Cheng Z, Li N, Mao S, Ma R, He H, Niu Z, Chen X, Xiang H*. The short- and long-term associations of particulate matter with inflammation and blood coagulation markers: A meta-analysis. Environment Pollution. (IF: 8.071) 2020 Dec;267:115630. doi: 10.1016/j.envpol.2020.115630.
18. Xie Y#, Xiang H#, Di N, Mao Z, Hou J, Liu X, Huo W, Yang B, Dong G, Wang C, Chen G, Guo Y, Li S. Association between residential greenness and sleep quality in Chinese rural population. Environment International. (IF: 9.621) 2020 Dec;145:106100. doi: 10.1016/ j.envint. 2020.106100.
19. Xiaolu Chen , Feifei Liu, Zhiping Niu, Shuyuan Mao, Hong Tang, Na Li, Gongbo Chen, Suyang Liu, Yuanan Lu, Xiang Hao*. The Association Between Short-Term Exposure to Ambient Air Pollution and Fractional Exhaled Nitric Oxide Level: A Systematic Review and Meta-Analysis of Panel Studies. Environmental Pollution (IF: 8.071), 2020 Jun 6;265(Pt A):114833. doi: 10.1016/j.envpol.2020.114833.
20. Mao Shuyuan#, Li Shanshan#, Wang Chongjian, Liu Yisi, Li Na, Liu Feifei, Huang Shuqing, Liu Suyang, Lu Yuanan, Mao Zongfu, Huo Wenqian, Chen Gongbo*, Xiang Hao*, Guo Yuming. Is long-term PM1 exposure associated with blood lipids and dyslipidemias in a Chinese rural population? Environment International (IF: 9.621), 2020, 138:105637
21. Li Na#, Chen Gongbo#, Liu Feifei, Mao Shuyuan, Liu Yisi, Liu Suyang, Mao Zongfu, Lu Yuanan, Wang Chongjian, Guo Yuming, Xiang Hao*, Li Shanshan. Associations between long-term exposure to air pollution and blood pressure and effect modifications by behavioral factors. Environmental Research (IF: 6.498), 2020, 182: 109109.
22. Jiayuan Hao, Zhiyi Yang, Shuqiong Huang, Wenwen Yang, Zhongmin Zhu, Liqiao Tian, Yuanan Lu, Hao Xiang*, Suyang Liu*. Acute effects of air pollution on the incidence of hand, foot, and mouth disease in Wuhan, China. Atmospheric Environment (IF: 4.798), 2020, 225: 117358.
23. WenyuanYu, Suyang Liu, JunfengJiang, GongboChen, HuijuanLuo, YuanshanFu, LinglingXie, BaojingLi, NaLi, ShuChen, Hao Xiang*, Shenglan Tang. Burden of ischemic heart disease and stroke attributable to exposure to atmospheric PM2.5 in Hubei province, China Atmospheric Environment (IF: 4.798), 2020, 15 January,Volume 221, 117079
24. Hao Jiayuan, Yang Zhiyi, Yang Wenwen, Huang Shuqiong, Tian Liqiao, Zhu Zhongmin, Lu Yuanan, Xiang Hao*, Liu Suyang*. Impact of Ambient Temperature and Relative Humidity on the Incidence of Hand-Foot-Mouth Disease in Wuhan, China. International Journal of Environmental Research and Public Health (IF: 3.390), 2020, 17(2): 428.
25. Liu F, Guo Y, Liu Y, Chen G, Wang Y, Xue X, Liu S, Huo W, Mao Z, Hou Y, Lu Y, Wang C, Xiang H*, Li S. Associations of long-term exposure to PM1, PM2.5, NO2 with type 2 diabetes mellitus prevalence and fasting blood glucose levels in Chinese rural populations. Environment International. (IF: 9.621) 2019:105213. doi:10.1016/j.envint.2019.105213.
26. Li N, Chen G, Liu F, Mao S, Liu Y, Hou Y, Lu Y, Liu S, Wang C∗, Xiang H∗, Guo Y, Li S. Associations of long-term exposure to ambient PM1 with hypertension and blood pressure in rural Chinese population: The Henan rural cohort study. Environment International. (IF: 9.621) 2019 Apr 26;128:95-102. doi: 10.1016/j.envint.2019.04.037.
27. Mao S, Chen G, Liu F, Li N, Wang C, Liu Y, Liu S, Lu Y, Xiang H*, Guo Y, Li S. Long-term effects of ambient air pollutants to blood lipids and dyslipidemias in a Chinese rural population. Environmental Pollution. (IF: 8.071) 2019 Oct 18:113403. doi: 10.1016/j.envpol. 2019. 113403.
28. Chen G#, Xiang H#, Mao Z, Huo W, Guo Y, Wang C, Li S. Is long-term exposure to air pollution associated with poor sleep quality in rural China? Environment International. (IF: 9.621) 2019 Dec;133(Pt B):105205. doi: 10.1016/j.envint.2019.105205
29. Hao J, Yang Z, Huang S, Yang W, Zhu Z, Tian L, Lu Y, Xiang H∗, Liu S∗. The association between short-term exposure to ambient air pollution and the incidence of mumps in Wuhan, China: A time-series study. Environment Research (IF: 6.498), 2019 Oct;177: 108660. Doi:0.1016/ j.envres.2019. 108660
30. Liu F, Chen G, Huo W, Wang C, Liu S, Li N, Mao S, Hou Y, Lu Y, Xiang H∗. Associations between long-term exposure to ambient air pollution and risk of type 2 diabetes mellitus: A systematic review and meta-analysis. Environment Pollution. (IF: 8.071) 2019 Sep;252(Pt B):1235-1245. doi: 10.1016/j.envpol.2019.06.033. Epub 2019 Jun 13.
31. Guan L, Gao P, Liu S, Liu Y, Li X, Liu F, Mao Z, Lu Y, Xiang H*. Development of a global health bachelor curriculum in China: a Delphi study. BMJ Open. (IF: 2.692) 2019 Jan 3;9(1):e023893. doi: 10.1136/bmjopen-2018-023893.
32. Qing Huang, Yunzhao Ren, Yisi Liu, Suyang Liu, Feifei Liu, Xiangyu Li, Baojing Li,Yitan Hou, Yuanan Lu, Shiyue Li, Hong Yan∗, Hao Xiang∗ Associations of gestational and early life exposure to air pollution with childhood allergic rhinitis. Atmospheric Environment (IF: 4.798) 2019 200: 190-196
33. Yunzhao Ren, Xing Yao, Yisi Liu, Suyang Liu, Xiao Li, Qing Huang, Feifei Liu, Na Li, Yuanan Lu, Zhanpeng Yuan, Shiyue Li, Hao Xiang* Outdoor air pollution pregnancy exposures are associated with behavioral problems in China’s preschoolers. Environmental Science and Pollution Research. (IF: 4.223) 2019 Jan;26(3):2397-2408. doi: 10.1007
34. Yu W, Jiang J, Xie L, Li B, Luo H, Fu Y, Chen S, Wu C, Xiang H*, Tang S. Mortality Trends in Colorectal Cancer in China During 2000-2015: A Joinpoint Regression and Age-Period-Cohort Analysis. Preventing Chronic Disease. (IF: 2.830) 2018 Dec 13;15:E156. doi: 10.5888/ pcd15.180329.
35. Chen S, Guo L, Wang Z, Mao W, Ge Y, Ying X, Fang J, Long Q, Liu Q, Xiang H, Wu C, Fu C, Dong D, Zhang J, Sun J, Tian L, Wang L, Zhou M, Zhang M, Qian M, Liu W, Jiang W, Feng W, Zeng X, Ding X, Lei X, Tolhurst R, Xu L, Wang H, Ziegeweid F, Glenn S, Ji JS, Story M, Yamey G, Tang S. Current situation and progress toward the 2030 health-related Sustainable Development Goals in China: A systematic analysis. PLoS Med. (IF: 11.069) 2019 Nov 19;16(11):e1002975. doi: 10.1371/journal.pmed.1002975.
36. Liu Xiaotian #, Tu Runqi#, Qiao Dou, Niu Miaomiao, Li Ruiying, Mao Zhenxing, Huo Wenqian, Chen Gongbo, Xiang Hao, Guo Yuming, Li Shanshan*, Wang Chongjian*. Association between long-term exposure to ambient air pollution and obesity in a Chinese rural population: The Henan Rural Cohort Study. Environmental Pollution (IF: 8.071), 2020, 260:114077.
37. Hou Jian, Liu Xiaotian, Tu Runqi, Dong Xiaokang, Zhai Zhihan, Mao Zhenxing, Huo Wenqian, Chen Gongbo, Xiang Hao, Guo Yuming, Li Shanshan*, Wang Chongjian*. Long-term exposure to ambient air pollution attenuated the association of physical activity with metabolic syndrome in rural Chinese adults: A cross-sectional study. Environment International (IF: 9.621), 2020, 136:10545
38. Pan Gao, Hao Xiang*, Suyang Liu, Yisi Liu, Shengjie Dong, Feifei Liu, Wenyuan Yu, Xiangyu Li, Li Guan, Yuanyuan Chu, Zongfu Mao, Shu Chen, Shenglan Tang. Evaluation of a consulting training course for international development assistance for health. BMC Medical Education, (IF: 2.463) 2018, 18:234
39. Li X, Huang S, Jiao A, Yang X, Yun J, Wang Y, Xue X, Chu Y, Liu F, Liu Y, Ren M, Chen X, Li N, Lu Y, Mao Z, Tian L, Xiang H*. Association between ambient fine particulate matter and preterm birth or term low birth weight: An updated systematic review and meta-analysis. Environmental Pollution. (IF: 8.071) 2017 Apr 27. pii: S0269-7491(16)32550-7. doi: 10.1016
40. Yuanyuan Chu, Yisi Liu, Yuanan Lu, Lichen Yu, Hanson Lu, Yulin Guo, Fengfeng Liu, Yanyan Wu, Zongfu Mao, Meng Ren, Na Li, Xi Chen, Hao Xiang*. Propensity to Migrate and Willingness to Pay Related to Air Pollution among Different Populations in Wuhan, China. Aerosol and Air Quality Research. (IF: 3.063) 2017, 17:752-760, doi: 10.4209/aaqr.2016.05.0178
